Fig. 3: Contributions of neurotransmitter receptors/transporters to ND factors.
A We construct four separate multilinear models of neurotransmitter receptors/transporters and each ND factor. The corresponding model goodness-of-fit (adjusted R2) is shown in the bar plot. B Dominance analysis was performed for each multilinear model to determine the relative importance of the predictors. The total dominance values, measuring the relative importance of the predictors, are shown. C We stratified receptors into excitatory and inhibitory receptors and calculated their accumulated contributions (by summing the total dominance values) to the ND factors. The accumulated contribution of excitatory receptors (Excitatory_Dtotal) was plotted against that of inhibitory receptors (Inhibitory_Dtotal). The gray line indicates the identity line. Note: PF1 positive factor 1, PF2 positive factor 2, NF1 negative factor 1, NF2 negative factor 2.
