Fig. 1: Transcriptional alterations occur during the progression of T2D. | Communications Biology

Fig. 1: Transcriptional alterations occur during the progression of T2D.

From: Transcriptional dynamics in type 2 diabetes progression is linked with circadian, thermogenic, and cellular stress in human adipose tissue

Fig. 1

a Normal-weight individuals (NW) (n = 7) were compared with overweight/obese (OW) individuals (S1) (n = 8), OW with prediabetes (PD) (S2) (n = 7), and OW with type 2 diabetes (T2D) (S3) (n = 8). b-c Volcano plots depict the identified DEGs in each stage and the number of up- or down-regulated DEGs in OW (S1), PD (S2), and T2D (S3), (P < 0.05, |log2(Fold Change)|>1.1). d–f Venn diagrams illustrate shared and exclusive DEGs in each stage.

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