Fig. 2: Identification of shared risk SNPs between BMI and PE. | Communications Biology

Fig. 2: Identification of shared risk SNPs between BMI and PE.

From: Elucidating shared genetic association between female body mass index and preeclampsia

Fig. 2

A Stratified Q-Q plots conditioned on BMI (left) and PE (right). B Manhattan plot of genetic associations between BMI and PE based on LAVA analysis. The x-axis represents chromosomal positions, and the y-axis shows −log10(conjFDR), indicating the statistical significance of genomic regions. The dashed line represents the significance threshold (−log10(FDR) = 2). Red points indicate significant loci with PFDR < 0.01, and yellow points denote the leading SNPs (representative single nucleotide polymorphisms). BMI body index mass, PE preeclampsia.

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