Fig. 7: Effect of FOXO4-DRI on localization of p53-pS15 and FOXO4 in senescent fibroblast model in vitro. | Communications Biology

Fig. 7: Effect of FOXO4-DRI on localization of p53-pS15 and FOXO4 in senescent fibroblast model in vitro.

From: FOXO4-DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53-serine 15 phosphorylation

Fig. 7

Double immunofluorescence staining of the serum limitation-induced senescent fibroblasts model from normal skin (a) and keloid (b) with or without FOXO4-DRI (25 μM) in medium for 3 days. p53-pS15 (Red) and FOXO4 (Green). The nucleus was counterstained with DAPI (Blue) (scale bar = 10 μm).

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