Fig. 4: Relative contribution of predicted functional groupings among genes influential to principal components (PC) 1, 3, 4, and 9.
From: Viral genomic features predict Orthopoxvirus reservoir hosts
For the most influential viral traits based on link prediction, we assigned predictive functions to genes with loading values greater than 1.5 times the standard deviation in the positive range or less than 1.5 times the standard deviation in the negative range (n = 89,128, 123, and 89, respectively). We then plotted counts for each gene category (ankyrins, virus structure and entry, virus replication and gene expression, host interactions and immune evasion or unknown function) for (a) PC1, (b) PC3, (c) PC4, and (d) PC9.
