Fig. 2: Regional comparison volcano plots showing transcripts upregulated and downregulated in secretory and ciliated ROIs in the discovery cohort. | Communications Biology

Fig. 2: Regional comparison volcano plots showing transcripts upregulated and downregulated in secretory and ciliated ROIs in the discovery cohort.

From: Spatial transcriptomic profiling of the human fallopian tube epithelium reveals region-specific gene expression patterns

Fig. 2

Volcano plots for secretory cell segments showing transcripts differentially expressed in (a) the fimbria, (b) the infundibulum, (c) the ampulla, and (d) the isthmus relative to all other regions. e) A summary of all transcripts observed upregulated and downregulated in the fallopian tube. Scale bar = 5 mm f) A summary of all transcripts observed upregulated and downregulated in ciliated cells. Scale bar = 5 mm g-j) Volcano plots for ciliated cell segments showing transcripts differentially expressed in (g) the fimbria, (h) the infundibulum, (i) the ampulla, and (j) the isthmus relative to all over regions. Red points: upregulated transcripts; blue points: downregulated transcripts, red lines: p-value cutoff (\({-{{\mathrm{log}}}}_{10}(p)=1.3\)); blue lines = FC cutoff (\({{{\mathrm{log}}}}_{2}({FC})\,=\,+/-\,0.5\)). Created in BioRender. Sipes, J. (2025) https://BioRender.com/p37o480.

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