Fig. 4: Differential expression of transcripts involved in cell-cell adhesion, ROS response, and apoptosis. | Communications Biology

Fig. 4: Differential expression of transcripts involved in cell-cell adhesion, ROS response, and apoptosis.

From: Spatial transcriptomic profiling of the human fallopian tube epithelium reveals region-specific gene expression patterns

Fig. 4

a–p Boxplots of transcripts differentially expressed in different anatomical regions of the fallopian tube, showing expression in both ciliated and secretory segments. Point shapes are chosen based on patient information. P-values for selected comparisons are plotted. All p-values are calculated using two-sided t-test. green: fimbria; blue: infundibulum, red: ampulla, purple: isthmus; circles: pt_1, squares: pt_2, diamonds: pt_3, Lower and upper hinges of boxplot correspond to first (Q1) and third quartiles (Q3); central line corresponds to median. Whiskers of boxplot range from Q3 + 1.5*IQR to Q1-1.5*IQR. Plots (a–h) show cell-cell adhesion transcripts expressed in the fallopian tube epithelium in the discovery (n = 77) (a–d) and validation cohorts (n = 74) (e–h). Plots (i–p) show transcripts associated with reactive oxygen species or apoptosis/cell cycle expressed in the fallopian tube epithelium in the discovery (i–l) and validation cohorts (m–p).

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