Fig. 1: Hypothesized time course of excitation-inhibition balance in AD-related decline. | Communications Biology

Fig. 1: Hypothesized time course of excitation-inhibition balance in AD-related decline.

From: Longitudinal excitation-inhibition balance altered by sex and APOE-ε4

Fig. 1

Schematic representation of a speculated excitation-inhibition (E/I) order of events during the course of Alzheimer’s disease (preclinical, MCI, and dementia) and associated protein pathologies (amyloid-β and tau). This representation was proposed by Koelewijn et al., based on converging preliminary studies. Created in BioRender. Duran, M. (2025) https://BioRender.com/d70o684.

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