Fig. 1: Potential target screening and functional enrichment analysis of Gardenia jasminoides J. Ellis components for treating depression. | Communications Biology

Fig. 1: Potential target screening and functional enrichment analysis of Gardenia jasminoides J. Ellis components for treating depression.

From: Nanocrystalline cellulose-geniposide complex enhances gut-brain axis modulation for depression treatment

Fig. 1

A Illustrative Overview of the Bioinformatics Analysis Process; B Venn Diagram Showing the Intersection Genes between Depression-Related Genes and Gardenia jasminoides J. Ellis Active Compound Target Genes; C Network Illustrating the Drug-Active Component-Target-Depression Relationship of Gardenia jasminoides J. Ellis, where green and red colors denote Gardenia jasminoides J. Ellis and Depression, respectively, yellow signifies 52 active compounds with target genes, and blue represents 47 intersecting target genes; D Hierarchical Tree Map displaying the enrichment of target genes in different GO categories (Biological Process, Cellular Component, Molecular Function); E Network Diagram of KEGG Pathway Enrichment Analysis; F Protein Interaction Node Statistics Chart of the 47 intersecting target genes; G PPI Network Graph based on the Degree value of the 47 intersecting target genes, wherein larger nodes with redder color indicate higher importance in the network, and thicker, redder lines denote stronger interaction relationships.

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