Fig. 1: Preparation and optimization of COL/NIC-mPEG-PLGA-NPs. | Communications Biology

Fig. 1: Preparation and optimization of COL/NIC-mPEG-PLGA-NPs.

From: Amphiphilic mPEG-PLGA copolymer nanoparticles co-delivering colistin and niclosamide to treat colistin-resistant Gram-negative bacteria infections

Fig. 1

a Preparation of nanoparticles using the double emulsification method. b–d The response surface model demonstrated the influence of mPEG-PLGA concentration, volume ratio of dichloromethane to acetone, and PVA concentration on nanoparticles NIC-EE (b), COL-EE (c), and size (d). e Effect of different lyoprotectants on COL/NIC-mPEG-PLGA-NPs.

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