Fig. 2: Schematic showing examples of spatiotemporal influence on PROTAC activity.
From: Cellular parameters shaping pathways of targeted protein degradation
A Spatial regulation of PROTAC-mediated AURKA degradation in mitotic cells. B Temporal regulation of PROTAC-mediated CDK2 degradation through the cell cycle. Created in BioRender. Cardno, A. (2025) https://BioRender.com/ud1xchr.
