Table 1 Predictive performance metrics comparison between two in vivo 3D platforms

From: Development of an AI model for DILI-level prediction using liver organoid brightfield images

Metrics

Human liver organoids

HepG2 spheroids

Recall

vNo-DILI-Concern

0.9016

0.5800

vLess-DILI-Concern

0.7500

0.6058

vMost-DILI-Concern

0.7808

0.8580

Specificity

vNo-DILI-Concern

0.8557

0.9416

vLess-DILI-Concern

0.9552

0.9243

vMost-DILI-Concern

0.9059

0.6429

Precision

vNo-DILI-Concern

0.7971

0.5370

vLess-DILI-Concern

0.7500

0.6923

vMost-DILI-Concern

0.8769

0.6429

F1 score

vNo-DILI-Concern

0.8462

0.5577

vLess-DILI-Concern

0.7500

0.6462

vMost-DILI-Concern

0.8261

0.8463

Accuracy

 

0.8234

0.7741

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