Fig. 6: Relative methylation rates of the H3K4 and H3K36 peptides by WT and mutant PRDM9 enzymes. | Communications Biology

Fig. 6: Relative methylation rates of the H3K4 and H3K36 peptides by WT and mutant PRDM9 enzymes.

From: Investigation and design of the dual specificity of the PRDM9 protein lysine methyltransferase

Fig. 6

Analysis of the autoradiography signal from the soluble peptide H3K4 (1–19) and H3K36 (26–44) methylation by PRDM9 (195–415) WT and mutant enzymes. a Relative methylation signal intensities of H3K4 and H3K36 peptide bands normalized to the WT H3K4 methylation signal. The bars show the average of 3 independent experiments (21 in the case of the WT enzyme), the error bars display SEM. b Representation of the H3K4/H3K36 methylation signal ratio. The data were taken from (a), the errors were propagated from (a).

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