Fig. 1: Aggregation of hPMSCs at the inflammatory site of ileitis in mice. | Communications Biology

Fig. 1: Aggregation of hPMSCs at the inflammatory site of ileitis in mice.

From: Human placenta mesenchymal stromal cells alleviate intestinal inflammation and repair intestinal barrier function by activating AMPK-FXR pathway

Fig. 1

A In vivo tracing of hPMSCs on days 1, 3, 5, 7, 14, and 21 after hPMSC injection. Labeled hPMSCs were detected with an IVIS imaging system. Brighter colors indicate increased cell accumulation. (n = 4 in each group). B Quantification of DiR fluorescent radiance in the whole body over time. C Images of DiR fluorescent radiance in different organs and concentrated on the inflamed portion of the whole gut. D Large numbers of hPMSCs migrated in the muscularis of the inflamed part of the whole gut (merge of histological and fluorescence images). Arrow: hPMSCs (10×, scale bar, 250 µm). Data were presented as mean ± standard deviation (SD).

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