Fig. 6: Amino acid distributions for key interface residues. | Communications Biology

Fig. 6: Amino acid distributions for key interface residues.

From: Conserved heavy/light contacts and germline preferences revealed by a large-scale analysis of natively paired human antibody sequences and structural data

Fig. 6: Amino acid distributions for key interface residues.The alternative text for this image may have been generated using AI.

For each key interface residue (<4.5 Å heavy atom distance in the PDB), we plot how often the position is seen in a given dataset (y-axis count), and on the bar, we color by proportion of amino acid types at that position. A Heavy chains from PDB. B Light chains from RCSB PDB. C Heavy chains from PairedAbNGS. D Light chains from PairedAbNGS.

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