Fig. 3: Minimal inhibitory concentrations and β-lactamase activities are positively correlated with cooperative resistance.

Correlations between the proportion of non-producers and MIC, total β-lactamase activity, and extracellular β-lactamase activity in the presence of PEN. Data is based on strains with bla genes in the chromosome (one copy) and the non-conjugative plasmids (multiple copies). A Correlations stratified by genes. Different colored lines indicate different β-lactamase genes, and dots represent different replicates (3 \(\le\) n \(\le\) 5). B Correlations not stratified by gene (all data pooled). Extracellular β-lactamase activity does not correlate positively with the proportions of non-producers.