Table 3 Top 5 differentially-expressed individual lipid levels in the forebrain and cerebellum of 18-month-old WT and ΔLYST-B6 mice

From: A murine model lacking Lyst recapitulates Chediak-Higashi syndrome with an earlier-onset neurodegenerative phenotype

Brain Region

Lipid

Ion

Log2(FoldChange)

P-value

Forebrain

MG(20:1) + NH4

Positive

−0.71

5.37E−6

Forebrain

Hex2Cer(d38:1)-H

Negative

−0.63

2.00E−5

Forebrain

Cer(d40:0 + O)-H

Negative

1.09

3.90E−5

Forebrain

MG(20:1)+Na

Positive

−0.74

2.45E−4

Forebrain

PS(40:7) + H

Positive

2.84

2.65E−4

Cerebellum

DG(28:1e)+NH4

Positive

1.51

1.90E−9

Cerebellum

BiotinylPE(34:6)-H

Negative

3.53

5.89E−8

Cerebellum

Cer(t36:1)-H

Negative

2.30

6.37E−8

Cerebellum

Hex1Cer(d44:2)-H

Negative

−1.11

4.27E−6

Cerebellum

PS(42:8)-H

Negative

1.87

4.41E−6