Table 4 Top 5 differentially-expressed genes from RNA-seq analysis of the forebrain and cerebellum in 3- and 18-month-old WT and ΔLYST-B6 mice
Brain Region | Age (Months) | Base Mean | Log2(FoldChange) | Adjusted P | Gene Name |
|---|---|---|---|---|---|
Forebrain | 3 | 1246 | −1.23 | 4.79E−32 | Btaf1 |
Forebrain | 3 | 2044 | 0.819 | 3.96E−23 | Pik3c3 |
Forebrain | 3 | 2628 | 0.806 | 1.37E−19 | Junb |
Forebrain | 3 | 594.4 | 1.34 | 2.65E−15 | Lmbr1 |
Forebrain | 3 | 967.5 | 0.936 | 1.78E−13 | Fos |
Cerebellum | 3 | 2349 | 1.28 | 4.10E−32 | Pik3c3 |
Cerebellum | 3 | 586.4 | 1.16 | 3.01E−07 | Lmbr1 |
Cerebellum | 3 | 98.51 | -7.09 | 2.69E−06 | Kpna7 |
Cerebellum | 3 | 803.4 | 0.833 | 1.06E−4 | Cd59b |
Cerebellum | 3 | 195.7 | 1.02 | 6.40E−4 | Npas4 |
Forebrain | 18 | 10830 | 1.07 | 2.78E−21 | Gfap |
Forebrain | 18 | 1347 | 0.770 | 2.69E−14 | H2-K1 |
Forebrain | 18 | 78.30 | 2.59 | 3.62E−11 | Clec7a |
Forebrain | 18 | 1288 | 0.695 | 1.70E−10 | Mpeg1 |
Forebrain | 18 | 2177 | 0.645 | 5.29E−10 | H2-D1 |
Cerebellum | 18 | 754.5 | 3.91 | 6.12E−78 | Gpnmb |
Cerebellum | 18 | 1536 | 2.66 | 8.81E−62 | Lyz2 |
Cerebellum | 18 | 475.8 | 3.17 | 2.23E−46 | C3 |
Cerebellum | 18 | 4358 | 1.83 | 3.99E−46 | C4b |
Cerebellum | 18 | 188.2 | 3.13 | 2.40E−39 | Lilrb4a |
