Fig. 4: Fine-grained areal-level IHFPs assigned to canonical 17-networks.

a Alternate functional 17-networks parcellation calculated by averaging the network-assigned IHFPs (with threshold from 98% to 86% in 2% decrements in Supplementary Fig. 3). Striped colors indicate parcels that are assigned to multiple networks during the assignment procedure. b Normative trajectories of global mean functional connectivity for each assigned network based on IHFPs and Yeo 17-network parcellations. These results indicate that the system-level normative model trajectories exhibit high reproducibility in IHFPs compared with group averaged parcellation. c Variability of normative trajectories of global mean functional connectivity, represented by the mean absolute deviation of each parcel’s global mean functional connectivity related to its corresponding functional network, regressed out the number of parcels assigned to each network. Compared to group averaged large-scale network parcellations, the normative model trajectories based on IHFPs exhibit spatial heterogeneity at the system level. Data points for constructing box plots were calculated as variability for each parcel’s trajectory corresponding to network-level trajectory.