Fig. 2: ERP components and the difference between fearful and neutral faces for individual groups.
From: Fear perception as a function of hemisphere- and time-specific dynamics in the medial temporal lobes
a Data and analysis for the P1. rTLR patients exhibited the least emotion differentiation (βEmotion × Group (rTLR) × ERP = −0.081, p = 0.025). b Data and analysis for the N1. lTLR patients exhibited larger emotion differentiation than the unweighted average across all groups (βEmotion × Group (lTLR) × ERP = −0.081, p = 0.040). c Data and analysis for the EPN. As a trend, lTLR patients exhibited larger emotion differentiation than the unweighted average across all groups (βEmotion × Group (lTLR) = −0.080, p = 0.084). d Data and analysis for the LPP. lTLR patients exhibited larger emotion differentiation than the unweighted average across all groups (βEmotion × Group (lTLR) × ERP = 0.094, p = 0.017). ERP curves depict mean amplitudes of the marked channel clusters for each group (n = 18 per group). The grey area indicates the time-window in which the ERP component was extracted from the channels marked in black. Difference topographies (fearful-neutral) are averaged across time-points within the respective time-window. Boxplots show differential (fearful-neutral) amplitudes extracted from the channel clusters, averaged across time. Whiskers indicate the interquartile range. The bold horizontal line indicates the distribution median. Dots indicate single-subject values. Black squares indicate the distribution mean. lTLR patients with apical resections (spared hippocampus, n = 5) are marked in blue. Brackets mark significant comparisons that specify significant differences and interactive effects of Group and Emotion (*p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001). Since significant emotion differentiation in lTLR patients was shifted forwards (βfearful - neutral = 0.106, p = 0.050, d = 0.410; Supplementary Fig. 2) and not found in the a priori defined cluster (βfearful - neutral = 0.119, p = 0.277, d = 0.185), the significance marking is depicted in brackets. Abbreviations: HC healthy controls, lTLR left temporal lobe resection, ns not significant, rTLR right temporal lobe resection.
