Fig. 2: Neurons in LIPd receive topographic input from a single site in LIPv but widespread input from within LIPd.

A A one-in-five series of parasagittal sections shows the distribution of labelled cells after a CTb injection into LIPd in the left hemisphere of one animal (M128L). Retrogradely labelled neurons can be found throughout the layers and the extent of LIPd, but there is only one clear cluster of labelled cells in LIPv that project to the injection site. The densest label in LIPd is medial to the injection site. The inset section shows the myelin definitions of LIPv and LIPd from an alternate series. Red cells are in supragranular layers I-IV, purple cells in infragranular layers V-VI; * denotes the injection site. See Fig. 3A as well as Supplementary Figs. 2 and 3 for histological images before annotation and further Gallyas sections. B The plots summarise the 3D-pattern of label (dorso-ventral; medio-lateral; supragranular and infragranular layers) across all three animals with a tracer injection into LIPd (denoted as filled black dot). M129 (*) received an injection of the retrograde tracer Fluorogold, M128 and M131 of CTb. All three animals show an LIPd-intrinsic, wide-spread network of neurons that project to the injection site in area LIPd itself. They also all show a single cluster of labelled cells in LIPv indicative of a topographic input from LIPv to LIPd. For M128L, we show section numbers in the density map relating to the sections in A. L – lateral, M – medial, D – dorsal, V – ventral, A – anterior, P – posterior.