Fig. 4: Neurons in LIPv receive wide-spread input from within LIPv and from several cell clusters in LIPd. | Communications Biology

Fig. 4: Neurons in LIPv receive wide-spread input from within LIPv and from several cell clusters in LIPd.

From: Anatomical circuits for flexible spatial mapping by single neurons in posterior parietal cortex

Fig. 4

A A one-in-five series of parasagittal sections shows the distribution of labelled cells following a CTb injection in LIPv (M140L). Retrogradely labelled neurons can be found in supra- and infragranular layers across LIPv. In LIPd, several clusters of labelled cells are seen throughout the medio-lateral extent of LIPd. The inset section shows the myelin definitions of LIPv and LIPd from an alternate series. Red cells are in supragranular layers 2–4, purple cells in infragranular layers 5 + 6 with largely similar results; * denotes the injection site. B Plots summarise the 3D-pattern of label across all three animals with a tracer injection into LIPv (at the LIPd/v border for M127L *). All three animals show an LIPv-intrinsic wide-spread network of neurons that project to the injection site as well as multiple clusters of labelled cells in LIPd projecting to LIPv. For M140L, we show section numbers underneath the density map related to the sections depicted in A. See Supplementary Fig. 4 for a histological image of M132L before annotation. L – lateral, M – medial, D – dorsal, V – ventral, A – anterior, P – posterior.

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