Fig. 2: Structural overview of nCoV400Fab in complex with dimerized SARS-CoV-2 N-CTD. | Communications Biology

Fig. 2: Structural overview of nCoV400Fab in complex with dimerized SARS-CoV-2 N-CTD.

From: Structural basis of a human antibody targeting SARS-CoV-2 nucleocapsid protein dimerization domain and interfering with RNA-binding

Fig. 2

a Overall crystal structure of two nCoV400Fab bound to the α-helix side of the dimerized N-CTD. The color scheme for the different structural elements is consistent throughout the paper. Three boxed regions mark the binding epitopes (Epitope 1–3). b The top view of the crystal structure. c The bottom view of the crystal structure showed that the nCoV400Fab interacted with the α-helix side of the N-CTD dimer.

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