Fig. 1: Breadth of mAb 1122A11 binding and inhibitory activity. | Communications Biology

Fig. 1: Breadth of mAb 1122A11 binding and inhibitory activity.

From: Structure and function of a cross-neutralizing influenza neuraminidase antibody that accommodates recent N2 NA Asn245 glycosylation

Fig. 1

a Heat map of 1122A11 binding (presented as area under the curve (AUC) with red representing highest binding and green lowest binding across all data) to recombinant NA proteins in the presence of calcium and magnesium in ELISA with positive control pan-NA antibodies 1G01, 1E01 and FNI9, as well as a negative isotype IgG1 control antibody. b Heat map of antibody inhibition (with red representing lowest IC50 concentration and green the highest IC50) to the same recombinant NA proteins in MUNANA assay with positive control antibody 1G01.

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