Fig. 3: Acute TNAP inhibition disrupts choline metabolism in adult wild-type mice. | Communications Biology

Fig. 3: Acute TNAP inhibition disrupts choline metabolism in adult wild-type mice.

From: TNAP dephosphorylates phosphocholine and phosphoethanolamine and participates in triglyceride transport from the liver to the bloodstream

Fig. 3

A Serum levels of choline, phosphocholine, and GPC measured by NMR and B correlation between serum levels of choline and phosphocholine. C Liver content of choline and phosphocholine measured by NMR. D Liver content of PC. E Liver content of GPC. F Correlation between liver content of choline and GPC. G Liver content of phosphatidylethanolamine. H Kidney content of ethanolamine. Results are shown as mean ± standard deviation. Data were tested on normality and on equal variances with the Shapiro–Wilk test and Levene test, respectively. Then, data were analyzed on appropriate parametric t-test or a nonparametric Mann–Whitney test.

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