Fig. 4: Acute TNAP inhibition affects liver metabolism in adult wild-type mice.

A Quantification of TG levels in serum and liver. B Quantification of NEFA levels in serum and liver. C Quantification of glucose levels in serum and liver. D RT-qPCR quantification of transcript levels in the liver. Results are shown as mean ± standard deviation. Data were tested on normality and on equal variances with the Shapiro–Wilk test and Levene test, respectively. Then, data were analyzed on appropriate parametric t-test or a nonparametric Mann–Whitney test. Fgf21 fibroblast growth factor21, Il1 interleukin-1, NEFA non-esterified fatty acid, TG triglyceride.