Table 1 Data collection and refinement statistics (molecular replacement)

Space group

C 2 2 21

 a, b, c (Å)

156.73 297.70 205.16

 α, β, γ (°)

90.00 90.00 90.00

Resolution (Å)

49.87 (3.35)

R_{meas (%)}

45.2 (152.3)

CC1/2 (%)

99.2 (39.9)

I/σI

7.25 (2.17)

Completeness (%)

99.2 (96.6)

Multiplicity

14 (12.2)

No. mol. /asymm. unit

5

Resolution (Å)

49.87 (3.35)

No. reflections (total)

967,611

No. reflections (unique)

69,172

R_work / R_{free (%)}

0.22 / 0.27

 Protein

18680

 Ligand/ion

591

 Water

39

 Protein

71.3

 Ligand/ion

128.74

 Water

35.88

 Bond lengths (Å)

0.005

 Bond angles (°)

0.838