Fig. 3: Inference of macroscale synaptic efficacy. | Communications Biology

Fig. 3: Inference of macroscale synaptic efficacy.

From: Probabilistic inference of social presence across brain scales reveals enhanced synaptic efficacy

Fig. 3: Inference of macroscale synaptic efficacy.

A Lateral-interception task outline. B The two experimental conditions in the task. C Covariance of ball and paddle trajectories in time, along the axis of interception. D Sample paddle movement trajectories. E Average paddle speed across conditions and subject groups (whiskers = 1.5 × IQR). Number of empirical observables in all panels (i.e., subjects) is n = 14 and n = 13 for the female and male subjects groups, respectively. F Sample functional connectivity from one participant. G Source time-courses of an example participant’s EEG. H Median of the integration of the two subject groups across the seven functional networks. I Structural connectivity template used for whole-brain simulations. J Sample simulation from the Jansen-Rit model. K Integration of random simulations used as the data feature for training the neural density estimators. L Pooled estimated posterior distribution of SEe in attentional networks across subject groups (whiskers = 1 × IQR, nsamples = 2000 for each observable data point). M Median of inferred SEe in female versus male subjects. N Correlation of between-condition ratios of inferred SEe with behavioral performance (average paddle speed).

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