Fig. 3: Mutational spectrum of DDR genes in the T. annulata infected samples.
From: Genomic characterization of host gene alterations in Theileria annulata-transformed leukocytes
a The Figure shows major DDR pathway-related genes altered in our samples and the frequency of their alteration in the six datasets. Synonymous mutations are marked with blue and non-synonymous with orange color. The impact of the mutations was marked with another two sets of colors, light orange represents the tolerated mutation, and red represents the deleterious mutations predicted from the SIFT score. Samples lacking any mutation for the genes are marked with gray color. *Represent the presence of missense variation. The frequency of each gene is represented at the end. b Lollipop image showing the mutations of the CHEK2 gene for all six samples along with the SIFT score. All six samples have multiple mutations representing non-synonymous (red) and synonymous(green). Four out of the six samples had deleterious mutations, marked by the SIFT score.
