Fig. 8: Molecular complementation with glycyrrhetinic acid (GlycA) and glycyrrhizin (GlyzN).

A Log2 fold change in relative abundance of significant microbiota traits from MEL-C for microbiotas from subjects 770 and 776 (S770, S776) from GG (minor) versus AA (major) genotypes in the Middle American Diversity Panel (MDP) and in pools of seed from AA genotypes with the addition of GlycA or GlyzN (1% weight/weight of seed powder) relative to the AA genotype pools alone; B scatter plots of the data shown in the heatmap in panel (A) comparing the MDP data versus the GlycA and GlyzN-spiked samples; Spearman correlation coefficient and p-value are indicated; shaded region represents the 95% confidence interval of the regression line.