Fig. 1: Dynamic changes in the conjunctival microbiome of mice aged between week 1 and 8 of neonatal development. | Communications Biology

Fig. 1: Dynamic changes in the conjunctival microbiome of mice aged between week 1 and 8 of neonatal development.

From: Microbial influx during early postnatal life fortifies the ocular surface and guards against allergic eye disease in mice

Fig. 1

a The average relative abundance at family level (top 10) of the conjunctiva across different developmental stages in mice (n = 10 per group). Negative controls include laboratory environmental samples (N-E), reagents used at the time of amplification (N-A) and blank extractions (N-EX). b Shannon index of the conjunctival microbiome across different developmental stages in mice. c Principal coordinate analysis plot generated using OTU metrics based on the Bray-Curtis dissimilarities. Each point represents a sample. d Networks of co-occurring bacterial OTUs in conjunctiva across the different developmental stages in mice, based on the correlation analysis. The co-occurring networks are colored by phylum. A red edge indicates a positive interaction between two individual nodes, while a blue edge indicates a negative interaction. e Tracking the source of conjunctival microbiome across different developmental stages in mice. Data are shown as mean ± SEM. **P < 0.01, ***P < 0.001 using the one-way ANOVA.

Back to article page