Table 2 Comprehensive summary of Arabidopsis thaliana outer kinetochore
From: The composition and structure of the outer kinetochore KMN complex is conserved across kingdoms
Arabidopsis gene ID | Arabidopsis Protein | Purified with the bait: | localisation at interphase | Homolog in mammals | Homolog in S. Cerevisiae | Mutant phenotype | reported in Arabidopsis | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
DSN1 Cter | DSN1 Nter | CSM1 Cter | CSM1 Nter | KNL1 Nter | ||||||||
MIS12 complex | AT3G27520 | DSN1 | x | x | x | x | x | centromeric | DSN1 | Dns1 | lethal | this study |
AT3G20070 | CSM1, TTN9 | x | x | x | x | x | centromeric | not found | Csm1 | lethal | this study. Zhang et al.58 | |
AT4G00525 | NSL1.1 | x | x | x | x | x | centromeric | NSL1 | Nsl1 | slight fertility reduction | this study | |
AT1G01715 | NSL1.2 | x | x | o | o | x | not tested | this study | ||||
AT4G19350 | NNF1 | x | x | x | x | x | centromeric | Nnf1 (PMF1) | Nnf1 | lethal | Allipra et al.29 | |
AT5G35520 | ATMIS12 | x | x | x | x | x | centromeric | MIS12 | mtw1 | lethal | Sato et al.33 | |
NDC80 complex | AT3G54630 | NDC80, HEC1 | x | x | x | x | x | centromeric | HEC1/Ndc80 | Ndc80 | lethal | Shin et al.34 |
AT3G48210 | SPC25 | x | x | x | x | x | centromeric | SPC25 | Spc25 | lethal | Shin et al.34 | |
AT3G08880 | MUN | x | x | x | x | x | centromeric | MUN1/Spc24 | Spc24 | lethal | Shin et al.34 | |
AT1G61000 | NUF2 | x | x | x | x | x | centromeric | NUF2 | nuf2 | lethal | Li et al.32 | |
KNL complexs | AT2G04235 | KNL1 | x | x | x | x | x | centromeric | KNL1 | Spc105 | lethal | this study/ Deng et al.30 He et al.31 |
AT3G23910 | ZWINT1.1 | x | x | x | x | x | centromeric | ZWINT1 | Kre28 | lethal | this study | |
AT3G24255 | ZWINT1.2 | x | x | x | x | x | not tested | wild-type like | this study | |||
AT2G20635 | BMF1 | x | x | x | x | x | centromeric | Bub1/Mad3 | Bub1/Mad3 | wild-type like | Komaki & Schnittger43 | |
AT1G15660 | CENPC | x | x | x | x | x | centromeric | CENPC | Mif2 | lethal | Ogura et al.42 | |
AT3G10180 | CENPE | x | x | o | o | x | centromeric | CENPE | not found | wild-type like | Tang et al.44 | |
AT1G69400 | BUB3.3 | x | x | o | o | x | not detected | BUB3 | Bub3/Pac9 | wild-type like | Komaki & Schnittger43 | |
AT4G15880 | ESD4 | x | x | x | x | x | nuclear membrane | weak plant | Murtas et al.53 | |||
AT1G19980 | – | x | x | x | x | x | not tested | not tested | ||||
AT3G57000 | – | x | x | o | x | o | not tested | not tested | ||||
