Fig. 3: Evaluation of the \((\widehat{FC})\)–MC patterns on the original data, with reference to the scores model (single-subject analysis).

(Upper panel) \(\widehat{{\mbox{FC}}}\)–MC scores with each dot color determined by the median of \(\widehat{{\mbox{FC}}}\) entries across the subject’s brain, alongside the \(\widehat{{\mbox{FC}}}\) matrices for two individuals exhibiting contrasting coupling behaviors (right and left insets). Only the significant \(\widehat{{\mbox{FC}}}\) entries, according to the salience map, are considered, and the network matrices are obtained by averaging the remaining entries in each block. (Lower panel) \(\widehat{{\mbox{FC}}}\)–MC scores with each dot colored according to the median of MC entries across the subject’s brain, alongside the MC matrices for two individuals exhibiting contrasting coupling behaviors (right and left insets). Particularly the MC entries are analysed separating those presenting positive or negative salience values, to focus attention on the associated areas. Only the significant MC entries, according to the PLSC salience map, are considered, and the network matrices are obtained by averaging the remaining entries in each block.