Fig. 4: Glioma patients’ effective-metabolic decoupling.
From: Brain metabolic-functional (de)coupling from health to glioma dysfunction

(Upper panel) Projection of patient’s latent scores onto the latent space for S–SUVR (left), \(\widehat{{\mbox{FC}}}\)–MC (right). Colored dots represent glioma patients, while black dots depict healthy controls. For patients the marker size is proportional to the tumor volume (TM, includes tumor core, i.e., contrast agent enhancing and non-enhancing regions). The shaded area represents the “normality-band” for the expected healthy coupling. (Lower panel) Corresponding tumor-weighted frequency map for outlier patients.