Table 2 Cubic polynomial models of age-related changes in harmonized corpus callosum tract density across functional networks

From: Network-specific corpus callosum aging and age-moderated cognitive associations using tract-to-region analysis

Network

N

R²

Linear β (SE)

Quadratic β (SE)

Cubic β (SE)

Cubic p

FDR q

Perm p

SalVentAttn

718

0.431

−0.156 (0.028)

0.0018 (0.0004)

−0.000007 (0.000002)

<0.001

<0.001

<0.001

SomMot

718

0.420

−0.142 (0.031)

0.0015 (0.0005)

−0.000006 (0.000002)

<0.001

<0.001

<0.001

DorsAttn

718

0.364

−0.098 (0.026)

0.0011 (0.0004)

−0.000004 (0.000002)

0.004

0.006

<0.001

Default

718

0.310

−0.089 (0.029)

0.0009 (0.0004)

−0.000003 (0.000002)

0.001

0.001

<0.001

Cont

718

0.307

−0.084 (0.027)

0.0008 (0.0004)

−0.000003 (0.000002)

0.049

0.057

0.001

Limbic

718

0.082

0.032 (0.012)

−0.0003 (0.0002)

0.000001 (0.000001)

<0.001

<0.001

<0.001

Vis

718

0.009

−0.018 (0.021)

0.0002 (0.0003)

−0.000001 (0.000001)

0.057

0.057

0.084

  1. All models include sex as covariate and site as fixed effect. FDR correction applied across 7 networks using Benjamini–Hochberg procedure.
  2. β unstandardized coefficient, SE standard error, Perm p permutation test p-value (1000 iterations).
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