Table 3 Pearson correlations between functional network-specific corpus callosum tract density and behavioral performance (Bonferroni-corrected)

From: Network-specific corpus callosum aging and age-moderated cognitive associations using tract-to-region analysis

Behavioral test

Network

Pearson’s r

R²

Cohen’s f²

p-value (Bonferroni)

RAVLT total recall

SalVentAttn

0.330

0.109

0.123

<0.001

RAVLT total recall

SomMot

0.306

0.093

0.103

<0.001

RAVLT total recall

Cont

0.306

0.093

0.103

<0.001

RAVLT total recall

Default

0.294

0.087

0.095

<0.001

RAVLT total recall

DorsAttn

0.277

0.077

0.083

<0.001

TMT-A (seconds)

DorsAttn

−0.324

0.105

0.118

<0.001

TMT-A (seconds)

SalVentAttn

−0.311

0.097

0.107

<0.001

TMT-A (seconds)

SomMot

−0.306

0.093

0.103

<0.001

TMT-A (seconds)

Cont

−0.288

0.083

0.090

<0.001

TMT-A (seconds)

Default

−0.266

0.070

0.076

<0.001

TMT-B (seconds)

DorsAttn

−0.205

0.042

0.044

<0.001

TMT-B (seconds)

SalVentAttn

−0.204

0.042

0.043

<0.001

TMT-B (seconds)

Default

−0.203

0.041

0.043

<0.001

TMT-B (seconds)

SomMot

−0.189

0.036

0.037

<0.001

TMT-B (seconds)

Cont

−0.183

0.034

0.035

<0.001

MoCA total score

SalVentAttn

0.205

0.042

0.044

<0.001

MoCA total score

SomMot

0.197

0.039

0.040

<0.001

MoCA total score

Default

0.194

0.038

0.039

<0.001

MoCA total score

Cont

0.191

0.036

0.038

<0.001

MoCA total score

DorsAttn

0.161

0.026

0.027

<0.001

Locomotion composite

SalVentAttn

0.192

0.037

0.038

<0.001

Locomotion composite

DorsAttn

0.189

0.036

0.037

<0.001

Locomotion composite

SomMot

0.189

0.036

0.037

<0.001

Locomotion composite

Default

0.185

0.034

0.035

<0.001

Locomotion composite

Cont

0.172

0.030

0.031

<0.001

Vocabulary (theta)

SomMot

−0.157

0.025

0.025

0.006

Vocabulary (theta)

Limbic

−0.154

0.024

0.024

<0.001

Vocabulary (theta)

DorsAttn

−0.143

0.020

0.021

0.011

NIH Pattern Comparison

SalVentAttn

0.156

0.024

0.025

0.017

  1. Only associations surviving Bonferroni correction for multiple comparisons are shown (p < 0.05; 29 of 56 tests). All correlations were validated by permutation testing with 10,000 iterations. R² = coefficient of determination; Cohen’s f² = effect size measure. Effect sizes classified as small (r = 0.10–0.30) or medium (r = 0.30–0.50). Negative correlations for Trail Making Tests indicate that lower completion times (better performance) are associated with higher tract density. Complete results for all 56 tested associations are provided in Supplementary Table S6.
  2. RAVLT Rey Auditory Verbal Learning Test, MoCA Montreal Cognitive Assessment, NIH National Institutes of Health, TMT Trail Making Test.
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