Fig. 5: Ratio distributions of cis and trans genes expression in aneuploid population.

A–I The X-axis represent chromosome 1 to 19, the Y-axis represent the ratio of aneuploid with extra chromosomes to diploid. Orange dots represent chromosomes with normal (two) copies, while green dots represent chromosomes with varied (three) copies. Compared with diploid level (red dotted line, with value of 1.0), the dosage effect was referred to expression of cis genes were higher than the diploid level, while the dosage compensation was referred to expression of cis genes were similar or lower than the diploid level. The inverse effect was referred to expression of trans genes were lower than the diploid level, while the positive inverse effect was referred to expression of trans genes were higher than the diploid level.