Table 1 Parameters used in OSR tuning (Fig. 2) and phenotype model comparison experiments (Figs. 3, 4)

From: SIMPLICITY is an agent-based, multi-scale mathematical model to study SARS-CoV-2 intra- and between-host evolution

Parameter

OSR tuning

Phenotype model comparison

Population size

1000

1000

Infected individuals at start

10

10

Final time (days)

1095

1095

τ3

7.5

7.5

R

1.1

1.1

Diagnosis rate

0.1

0.1

IH virus emergence rate (kv)

0

0

Nucleotide substitution rate (e)

[10−6, 3 × 10−4]

0.00008759

Phenotype model

immune_waning

baseline, immune_waning

Sequencing rate

0.05

0.05

Seeded simulations number

100

300