Table 1 A summary of proteomic and histone-specific proteomic coverage of cells analyzed at each relative number of cells per day

From: Simultaneous single-cell proteomics and epigenetic analysis of histone deacetylase inhibition in human cells

LCMS injections/day (SPD)

30 SPD

60 SPD

100 SPD

200–500 SPD

Column length

15 cm

8 cm

8 cm

4 cm

Cells per day after controls

210CPD

420CPD

700CPD

1400–3500CPD

Total protein groups

1395

1755

964

171

Average # proteins/cell

342.97

453.51

215.52

NA

Maximum # proteins/cell

858

811

387

NA

Unique histone proteins

14

16

15

9

Total histone PSMs

4284

8022

3355

163

Average % coverage of histones

47%

44%

41.70%

22.11%

Cells analyzed

280

567

378

84