Fig. 2: Whole-cell catalysis for PGF2α production in Y. lipolytica.

A Diagram of PGF2α synthesis from ARA via whole-cell catalysis system. B PGF2α production in the original and engineered strains. C PGF2α production in the engineered strain PG02 under different ARA concentrations (nmol/L). D PGF2α production in the engineered strain PG02 grown on 100 μM ARA under time-course fermentation. Pairwise comparisons were analyzed by Student’s t-test. ***P < 0.001. n = 3.