Fig. 5: Cofactor engineering improved PGF2α production in Y. lipolytica. | Communications Biology

Fig. 5: Cofactor engineering improved PGF2α production in Y. lipolytica.

From: Improved de novo production of prostaglandin F2α from glucose with engineered Yarrowia lipolytica strains

Fig. 5: Cofactor engineering improved PGF2α production in Y. lipolytica.The alternative text for this image may have been generated using AI.

A Diagram of cofactors for improving PGF2α synthesis in the engineered Y. lipolytica. The colored green lines represent the overexpressed genes for enhancing acetyl-CoA supply, and the colored blue lines represent the overexpressed genes for enhancing NADPH supply. B PGF2α production in engineered different Y. lipolytica strains. C NADPH levels in engineered different Y. lipolytica strains. D Acetyl-CoA levels in engineered different Y. lipolytica strains. Pairwise comparisons were analyzed by Student’s t-test. *P < 0.05, **P < 0.01. n = 3.

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