Fig. 4: Functional enrichment analysis reveals cluster-specific biological processes and epigenetic signatures associated with differentially methylated regions in metastatic and SDHB-mutant PPGLs. | Communications Biology

Fig. 4: Functional enrichment analysis reveals cluster-specific biological processes and epigenetic signatures associated with differentially methylated regions in metastatic and SDHB-mutant PPGLs.

From: Epigenetic and metabolic rewiring in metastatic pheochromocytomas and paragangliomas driven by SDHB mutations

Fig. 4: Functional enrichment analysis reveals cluster-specific biological processes and epigenetic signatures associated with differentially methylated regions in metastatic and SDHB-mutant PPGLs.

Bubble plots showing the top 5 most significant gene ontology (GO) biological processes (a), GO molecular functions (b), chemical and genetic perturbation gene sets (c), and cell-type–specific gene expression signatures (d) for the indicated clusters.

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