Fig. 6: Application of mECM in nerve.
From: Mesenchymal stem cell-derived extracellular matrix for musculoskeletal tissue regeneration

A Neuron hierarchical structure142. B mECM promotes axonal growth in the rat sciatic nerve and reinnervation of the muscles (tibialis anterior and gastrocnemius). Ⅰ A schematic illustrating the mechanisms through which mECM promotes nerve regeneration. Ⅱ BM-MSCs-ECM enhanced the axonal outgrowth in the dorsal root ganglions (DRGs). Ⅲ BMSC-ECM-NG promotes nerve regeneration and further myelin regeneration123.