Table 1 Features of transductions by their source L1s

From: Nanopore sequencing reveals hidden landscape of short L1 transductions in colorectal cancer

 

Somatic insertions

Median length

Median L1 content (%)

5´inversion rate (%)

Orphan rate (%)

Mode unique sequence in bp (n = transductions)

6p24.1-1

78

342

86

33

10

78 (18)

Xp22.2-1

72

492

91

28

3

37 (31)

22q12.1-1

34

588

7

41

50

818 (7)

7q21.3-2

24

296

83

21

8

61 (15)

4p15.31-1

18

426

95

22

0

72 (7)

8q24.21-1

13

457

92

23

8

85 (9)

14q23.1-1

11

437

50

27

36

671 (9)

6q25.3-1

11

618

22

46

46

NA

  1. Eight most somatically active L1 elements are shown in the table. The table shows the number of somatic insertions per source L1, their median length, the median L1 content in insertion, 5´ inversion rate, the rate of orphan transductions in the insertions and mode length of unique sequence, where insertions that share the modal unique sequence length is in parenthesis. Mode length for 6q25.3-1 is not reported, as all the transduced sequences were of different lengths.