Fig. 3: Transcription factor activity shapes cell type-specific gene regulation.
From: Chromatin accessibility landscapes define stromal cell identities across tissues
A Highly variable chromatin-accessible regions across annotated cell types. B Predicted transcription factor motifs enriched in accessible regions, grouped by motif family. C Transcription factor footprints for Klf1 in intestinal cell types such as goblet cells, enterocytes, and Paneth cells (indicated with asterisks) and for Runx1 in immune cell types, such as T cells and dendritic cells (indicated with asterisks), highlighting tissue-specific motif activity. D Dot plot displaying the top highly regulated genes in representative annotated cell types from each of the nine investigated tissues.
