Fig. 5: Intranasal OT ameliorates the innate defensive behavior deficit induced by LSD. | Communications Biology

Fig. 5: Intranasal OT ameliorates the innate defensive behavior deficit induced by LSD.

From: Early life adversity impairs visually evoked innate defensive behaviors via oxytocin signaling

Fig. 5: Intranasal OT ameliorates the innate defensive behavior deficit induced by LSD.The alternative text for this image may have been generated using AI.

Comparison between intranasal OT-treated LSD mice and control mice of the (a) latency to refuge, b representative images of trajectories, c distance ratio, d speed (black line represents looming stimulus presentation), e mean return speed, f maximum speed, and g time spent in the refuge after looming (n = 38 trials from 13 mice for the Ctrl+Saline, n = 39 trials from 13 mice for Ctrl+OT group, n = 42 trials from 14 mice for the LSD+Saline and LSD + OT group; Mann-Whitney U-test, *p < 0.05, **p < 0.01, ***p < 0.001).

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