Fig. 4: Hypothetical model of the T4P machinery in the non-piliated state. | Communications Biology

Fig. 4: Hypothetical model of the T4P machinery in the non-piliated state.

From: Structural insights into the Thermus thermophilus type IV pilus machinery assembling two distinct pili

Fig. 4: Hypothetical model of the T4P machinery in the non-piliated state.

a Slices through PilQ-masked and C1 density-masked sub-tomogram average maps, aligned at the P1/P2 density, with all protein densities and corresponding protein labels shown. The text colours of the protein names match the colours of the corresponding structures in (b). b Hypothetical models docked into the non-piliated state sub-tomogram average maps, from left to right: complete model in the maps, model alone without the maps, and a central slice of the model revealing the gates in PilQ (red). Numbered boxes indicate views enlarged in (c, d), focusing on: (1) the upper gate (G1) of PilQ, (2) the P1/P2 density (PilW), and (3) the cytoplasmic membrane assembly platform PilM, PilN, PilO and PilC. Different rotated views are shown. OM, outer membrane; PG, peptidoglycan; CM, cytoplasmic membrane; TM, transmembrane domain (green).

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