Fig. 1: Single Cell RNA-seq of mouse ovaries.
A Schematic of the ovary, highlighting the structural components and cell types identified and characterized in this study and their locations within the tissue. B UMAP plot of integrated young and old ovary single-cell datasets. C Violin plots of canonical cell-type marker genes used to classify clusters to cell types. D Changes in the proportion of cells in clusters from panel B between the young and old datasets. Error bars indicate the 95% confidence interval for the magnitude of the difference between ages as determined by bootstrapping. Dashed lines indicate absolute log2-fold changes greater than 0.58, and false discovery rate less than 0.05. Gray points indicate no significant difference between ages.
