Fig. 1: Single-molecule force-extension experiments.
From: Compliant mechanical response of the ultrafast folding protein EnHD under force
a Representation of the crystal structure of the EnHD domain. b Scheme of the experimental setup. The EnHD is sandwiched between two titin homodimers, deposited in solution over a gold surface, and dragged by the AFM cantilever, resulting in the unfolding of the proteins. c Force-extension trace including the characteristic sawtooth pattern for the titin domains, and the initial featureless signal for EnHD. Stretching is conducted at a speed of 40 nm s−1.
