Fig. 2: Variants in the TTN, PLN and STRN loci show distinct effects on LV morphology.

a–c, Manhattan plots for LV latent variables with best association for SNPs at the PLN (a), TTN (b) and STRN (c) loci. On top are shown the average meshes corresponding to the following range of quantiles, for each latent variable (from left to right): [0, 0.01], [0.095, 0.105], [0.495, 0.505], [0.895, 0.905] and [0.99, 1].